Endocrine Abstracts

Introduction: Neurofibromatosis type 1 (NF1) is one of the most frequent genetic dominant syndrom in men with a prevalence of 1 in 2600 to 3000 individuals worldwide. NIH NF1 diagnostic criteria are driven by the most frequent manifestations of the disease (café au lait macules (CAL), neurofibromas, freckling, optic glioma, Lisch nodules and osseus lesions). There are many clinical manifestations of NF1 (neurological, cardiovascular, gastrointestinal, endocrine and orthop...

Introduction: Neurofibromatosis type 1 (NF1) is one of the most frequent genetic dominant syndrom in men with a prevalence of 1 in 2600 to 3000 individuals worldwide. NIH NF1 diagnostic criteria are driven by the most frequent manifestations of the disease (‘café au lait’ macules (CAL), neurofibromas, freckling, optic glioma, Lisch nodules and bone lesions). There are many clinical manifestations of NF1 (neurological, cardiovascular, gastrointestinal, endocrine ...

A 65 year old patient who was hospitalised for a reactive arthritis of the knee due to Rickettsia infection, presented an asymptomatic persistant chronic hypocalcemia and hyperphosphoremia. In her medical history, we noted a hypertension treated with amlodipine and bisoprolol, syndrome of sleep apnoea, acquired lumbar spinal canal stenosis and sequelae of poliomyelitis acquired at 10 years of age in Congo, her place of origin. According to her blood test results, total calcium...